Answers to allergic reactions: the culprit is just one protein

Source: Pixabay

Since almost everyone is allergic to something or the other, this study would seem interesting to all.

Researchers from Johns Hopkins and University of Alberta have discovered that a single protein is the cause of all allergic reactions to medications and other substances. MRGPRX2 is the culprit protein that causes all the dangerous and painful allergic reactions.

“It’s fortunate that all of the drugs turn out to trigger a single receptor-it makes that receptor an attractive drug target,” says Benjamin McNeil, Ph.D., a postdoctoral fellow at Johns Hopkins University. If a new drug targeting this specific protein is found, it would be the answer to solving all allergic reactions. The study was published in the high impact journal, Nature.

The published article can be read here.

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Scientist-entrepreneur-manager-journalist: -Co-founder, Author; Former Assistant Editor and Director, Biotechin.Asia, Biotech Media Pte. Ltd.; -Founder & CEO, SciGlo (; -Programme Management Officer, SBIC, A*STAR (former Research Fellow). --Sandhya graduated from University of Madras, India (B.Sc Microbiology and M.Sc Biotechnology) and received her Ph.D from the Nanyang Technological University, Singapore. She worked on oxidative stress in skin, skeletal, adipose tissue and cardiac muscle for a decade from 2006-2016. She is currently working as a Programme Management Officer handling projects and grants at Singapore Bioimaging Consortium (SBIC), Agency for Science, Technology and Research (A*STAR). Earlier to this she was a Research Fellow in the Fat Metabolism and Stem Cell Group at SBIC. Sandhya was also the Vice President and Publicity Chair of A*PECSS (A*STAR Post Doc Society) (2014-2016). Recently she founded a platform for scientists - SciGlo ( and is a startup mentor at Vertical VC (Finland). She is an ardent lover of science and enjoys globe trotting and good vegetarian food.