Researchers from USA and Russia have found a cure for baldness using stem cells. They derived hair-inducing dermal papillae (DP)-like cells from human embryonic stem cells (hESCs) by first generating neural crust (NC) cells. They further proved that these hESC-derived DP-like cells (hESC-DPs) express molecular markers typically found in adult human DP cells. These cells were able to induce hair follicle formation when transplanted under the skin of immunodeficient nude mice. You might ask as to why we can’t use DP cells directly in transplantation. Human DP cells are not suitable for this purpose because they cannot be obtained in necessary amounts and they rapidly lose their ability to induce hair follicle formation when cultured in vitro. Lot of procedures including hair implants are in place nowadays, but there is still a lot of scope in the field of hair regeneration. These hESC-DPs might be answer to solve the problem of baldness.
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