Innovations in treating various cancers are a critical need to this day. Assistant Professor Edward Chow and his team from Cancer Science institute, Yong Loo Lin School of Medicine, National University of Singapore have established with the use of nanotechnology, a way to repurpose the existing chemotherapy drugs as an effective means against those cancer cells that escape chemotherapy treatment (chemoresistance). Chemoresistance is one of the major reasons for the failure of cancer treatments. New treatment paradigms to overcome this hurdle is the need of the hour.
Scientists attached nanodiamonds to Epirubicin, which is a widely used chemotherapy drug, thereby developing a drug delivery complex called nanodiamond-epirubicin nano delivery complex (EPND). This complex which is about 4-5 nanometers in size, has the ability to kill normal cancer cells and chemoresistant cells as opposed to just using epirubicin which can also act on normal cancer cells.
Compared to the conventional methods of cancer therapy, this delivery system using nanodiamonds is safer, effective and a boon for those patients who suffer from the side effects of standard chemotherapy. Though this delivery system is currently tested only on liver cancer, the versatility of the nanodiamonds offers a promising approach to treat a wide range of cancers.
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